If you’ve been around and used R/C planes for a while, you’ve probably lost an aircraft due to frequency interference. That was simply a hazard of the hobby when we were using frequencies on the 72 MHz range.
I personally had an aircraft I was rather fond of that fell victim to interference. The plane was a beautiful Grumman F7F Tigercat that Hobby Lobby used to sell. This wasn’t an ARF aircraft either. In fact, I had spent many man hours building, covering, and painting to get this twin engine, post WWII fighter plane looking and performing the way I wanted it to.
I took it out to one of our local flying fields, just like I had done many times in the past. This day just happened to be the day I was destined to experience pretty heavy radio interference from someone who must walked onto the field and tuned into the same frequency I was using before checking to see if anyone was on it. 
The crash that ensued resulted in at least seven to eight hundred dollars in broken parts. It wasn’t a total loss considering that the motors, airframe, and a few servos survived. But, what didn’t survive was the time and care I had put into assembling her just the way I wanted to. Luckily I know I won’t run into these issues again, thanks to the 2.4 GHz technology built into my Spektrum Radios.